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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | José Mendoza | 62 | 1904-1909 | |
| 2 | Arnaldo Rivera | 52 | 1905-1912 | |
| 3 | Jacinto Preciado | 43 | 1904-1913 | |
| 4 | Luis Castro | 40 | 1906-1914 | |
| 5 | Marco Zúñiga | 38 | 1903-1912 | |
| 6 | Admeto Sánchez | 36 | 1906-1913 | |
| 7 | Héctor Gutiérrez | 33 | 1903-1912 | |
| 8 | Teófilo Santiago | 31 | 1905-1911 | |
| 9 | Ildefonso González | 30 | 1907-1912 | |
| 10 | Remigio López# | 29 | 1903-1907 | |
| 11 | Ignacio Delgado# | 28 | 1907-1914 | |
| 11 | Camulógeno Ibarra# | 28 | 1903-1914 | |
| 13 | Ignacio Mandoza | 27 | 1905-1912 | |
| 13 | Miguel Rodríguez# | 27 | 1903-1914 | |
| 15 | Jimeno Flores | 22 | 1901-1910 | |
| 16 | Jacobo de Herrera | 21 | 1901-1905 | |
| 16 | Larry Muir | 21 | 1901-1911 | |
| 16 | Sarpedón Reyes# | 21 | 1910-1912 | |
| 19 | Roque Arreola | 20 | 1911-1914 | |
| 19 | Ray Cowley | 20 | 1901-1909 | |
| 21 | Javier Muñoz# | 19 | 1907-1914 | |
| 22 | Alejandro Alfaro | 18 | 1901-1907 | |
| 23 | Wayne Wood# | 17 | 1912-1913 | |
| 24 | Raúl Villarreal# | 16 | 1912-1914 | |
| 25 | Nicolás Lara | 15 | 1901-1910 | |
| 26 | Enda Hill# | 14 | 1911-1913 | |
| 27 | Gualterio Zavala | 13 | 1901-1910 | |
| 28 | Ernesto Aguilar# | 12 | 1912-1914 | |
| 28 | Mike Cox | 12 | 1901-1909 | |
| 28 | Adrián Moreno | 12 | 1903-1911 | |
| 31 | Dionisio Carmona# | 11 | 1913-1914 | |
| 32 | Adam Benoit | 9 | 1913-1914 | |
| 32 | Bob Brisson# | 9 | 1913-1914 | |
| 32 | Enrique Cabrera# | 9 | 1910-1914 | |
| 32 | Leví García | 9 | 1903-1910 | |
| 32 | Lino González# | 9 | 1910-1913 | |
| 32 | Melquíades Guzmán# | 9 | 1910-1911 | |
| 38 | Ricardo Alba# | 8 | 1913-1914 | |
| 38 | Theodor Klug# | 8 | 1911-1913 | |
| 38 | Ernesto Minaya | 8 | 1901-1912 | |
| 38 | Huáscar Morán | 8 | 1903-1911 | |
| 38 | Gamaliel Pérez | 8 | 1906-1911 | |
| 43 | Ricardo de Hoyos# | 7 | 1914-1914 | |
| 43 | Tobías Fuentes# | 7 | 1914-1914 | |
| 43 | Laurent Joly# | 7 | 1911-1914 | |
| 43 | Maxime Petit# | 7 | 1913-1914 | |
| 47 | Daryl Garland | 6 | 1914-1914 | |
| 47 | Cástor Rico | 6 | 1901-1905 | |
| 47 | Ramón Rivera# | 6 | 1910-1914 | |
| 50 | Troilo Basulto | 5 | 1903-1910 | |
| 50 | Leonel Carrizales | 5 | 1906-1913 | |
| 50 | Álvaro Hernández# | 5 | 1910-1914 | |
| 50 | Gustavo Villarreal | 5 | 1901-1904 | |
| 50 | Lucio Vélez | 5 | 1903-1912 | |
| 50 | Marco Zamora | 5 | 1901-1905 | |
| 56 | Michael Buhagiar# | 4 | 1914-1914 | |
| 56 | Tobias Felismino# | 4 | 1913-1914 | |
| 56 | Pascual Jiménez# | 4 | 1906-1912 | |
| 59 | Eunosto de Aza# | 3 | 1910-1912 | |
| 59 | Danilo García | 3 | 1909-1910 | |
| 59 | Scanlon Leonard# | 3 | 1911-1914 | |
| 59 | Milán Udris | 3 | 1901-1901 | |
| 63 | Eduardo Barron | 2 | 1908-1912 | |
| 63 | Zef Buzoku# | 2 | 1913-1914 | |
| 63 | Harman Charron | 2 | 1912-1914 | |
| 63 | Lee Fraser# | 2 | 1912-1914 | |
| 63 | Billy Fulleron | 2 | 1913-1914 | |
| 63 | Fergus Kerridge# | 2 | 1912-1913 | |
| 63 | Ismael Lucio | 2 | 1901-1903 | |
| 63 | Ray O'Brien | 2 | 1913-1914 | |
| 63 | Horacio Ramírez# | 2 | 1911-1913 | |
| 63 | Declan Robinson# | 2 | 1913-1914 | |
| 63 | Luis Salgado# | 2 | 1912-1914 | |
| 74 | Pascual Aguirre | 1 | 1901-1910 | |
| 74 | Ricardo Bobila | 1 | 1901-1903 | |
| 74 | Kyran Brune | 1 | 1914-1914 | |
| 74 | Dalmacio Campos | 1 | 1901-1906 | |
| 74 | Dustin Conway | 1 | 1901-1910 | |
| 74 | Pedro Estrada# | 1 | 1913-1913 | |
| 74 | Eduardo Flores | 1 | 1913-1913 | |
| 74 | Mercuriano Flores# | 1 | 1912-1913 | |
| 74 | Yoshiki Funaki# | 1 | 1914-1914 | |
| 74 | Gaspar García | 1 | 1904-1911 | |
| 74 | Ticiano Juvera | 1 | 1901-1905 | |
| 74 | Lester Long# | 1 | 1912-1914 | |
| 74 | Chris McRae | 1 | 1901-1904 | |
| 74 | Tiberio Márquez | 1 | 1910-1910 | |
| 74 | Tomás Márquez | 1 | 1901-1903 | |
| 74 | Beni Olba | 1 | 1901-1903 | |
| 74 | Nicasio Palacios | 1 | 1914-1914 | |
| 74 | Kellagh Taylor# | 1 | 1913-1913 | |
| 74 | Pirro Villarreal# | 1 | 1913-1914 | |
| 74 | José Zapata# | 1 | 1913-1914 | |
| 94 | Kendrick Ball | 0 | 1901-1901 | |
| 94 | Armando Barrera | 0 | 1906-1909 | |
| 94 | Roodan Bell# | 0 | 1912-1914 | |
| 94 | Francisco Bernabé | 0 | 1901-1903 | |
| 94 | José Bustos | 0 | 1901-1908 | |
| 94 | Zenón Cossio | 0 | 1901-1909 | |
| 94 | Gilberto Cruz | 0 | 1910-1910 |
