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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | WHIP | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Marco Antonio Santana# | 0.78 | 1905-1908 | |
| 2 | Fernando Chávez# | 1.03 | 1903-1908 | |
| 3 | Félix Castillo | 1.06 | 1901-1904 | |
| 3 | Saturnín Juárez# | 1.06 | 1901-1908 | |
| 5 | Álvar Ramírez# | 1.09 | 1901-1908 | |
| 6 | Carmelo Ramírez# | 1.10 | 1905-1908 | |
| 7 | Roberto Rosado# | 1.15 | 1902-1908 | |
| 7 | Goliat Portillo# | 1.15 | 1901-1908 | |
| 7 | Jaime Ramírez# | 1.15 | 1904-1908 | |
| 10 | Cole Farrell | 1.18 | 1901-1905 | |
| 11 | Julián Rodríguez# | 1.23 | 1905-1906 | |
| 12 | Bernal Lupercio# | 1.25 | 1901-1908 | |
| 12 | Ángel Rivera# | 1.25 | 1903-1908 | |
| 12 | Roberto Zúñiga# | 1.25 | 1904-1908 | |
| 15 | Fidel Paredes# | 1.30 | 1905-1908 | |
| 15 | Jesús García# | 1.30 | 1901-1907 | |
| 17 | Emanuel González# | 1.31 | 1905-1908 | |
| 17 | Isidoro Núñez# | 1.31 | 1906-1908 | |
| 19 | Tarasio Martínez# | 1.32 | 1906-1908 | |
| 20 | Fulgencio Meraz | 1.33 | 1901-1905 | |
| 20 | Norberto Luján | 1.33 | 1901-1905 | |
| 20 | Juan Santos# | 1.33 | 1906-1908 | |
| 23 | Adrián López# | 1.36 | 1906-1908 | |
| 24 | Catulo González# | 1.37 | 1905-1908 | |
| 25 | Serafín Villanueva# | 1.38 | 1905-1908 | |
| 25 | Jim Cole# | 1.38 | 1901-1908 | |
| 27 | Juan Robles | 1.45 | 1901-1903 | |
| 28 | Álvar Nieves# | 1.49 | 1901-1906 | |
| 29 | Justin Rau# | 1.62 | 1901-1905 |
