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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Servio González# | 190 | 1906-1915 | |
| 2 | An Thu | 158 | 1901-1912 | |
| 3 | Leoncio Savala# | 145 | 1906-1913 | |
| 4 | Timoteo de Armas# | 119 | 1905-1911 | |
| 5 | Kyle Gardiner# | 96 | 1901-1914 | |
| 6 | Rubén León# | 84 | 1911-1915 | |
| 7 | Mateo Zavala | 76 | 1902-1910 | |
| 8 | Jesús María Sánchez# | 63 | 1902-1914 | |
| 9 | Esdras Jiménez | 60 | 1903-1911 | |
| 9 | Pascual Reyes | 60 | 1901-1911 | |
| 11 | Diego González# | 59 | 1907-1913 | |
| 11 | Aurelio Rodríguez# | 59 | 1907-1914 | |
| 13 | Ademar Cisneros | 57 | 1907-1914 | |
| 14 | Ildefonso Torres | 51 | 1901-1911 | |
| 15 | Édgar Burgos | 48 | 1906-1911 | |
| 16 | Moisés del Campo# | 42 | 1905-1911 | |
| 17 | Eumeo Esquer | 36 | 1903-1914 | |
| 18 | Lorenzo Sena | 35 | 1901-1909 | |
| 19 | Ramón Urías# | 34 | 1906-1911 | |
| 20 | Argimiro Liceaga# | 33 | 1903-1915 | |
| 20 | Teodoro Luna | 33 | 1905-1913 | |
| 20 | Carlos Rodríguez | 33 | 1907-1913 | |
| 23 | Josías Godínez | 31 | 1901-1910 | |
| 23 | Justo Santana# | 31 | 1904-1911 | |
| 25 | Vicente Martínez | 30 | 1904-1912 | |
| 25 | Eufemio Sánchez# | 30 | 1910-1915 | |
| 27 | Sabino Gómez | 28 | 1904-1913 | |
| 28 | Matt Clark | 27 | 1901-1904 | |
| 28 | Elías Hinojos | 27 | 1903-1913 | |
| 30 | Vidal Checo | 25 | 1907-1912 | |
| 31 | José Padilla# | 24 | 1912-1915 | |
| 31 | Lorenzo Salas | 24 | 1901-1908 | |
| 31 | Vicente Tirado | 24 | 1902-1913 | |
| 34 | Bill Anderson | 23 | 1903-1912 | |
| 34 | Ramiro Escareóo | 23 | 1901-1908 | |
| 34 | Hefesto Muñoz# | 23 | 1912-1912 | |
| 34 | Diego Polanco | 23 | 1906-1911 | |
| 38 | Guillermo Pagán# | 22 | 1909-1915 | |
| 38 | Gaël Rey# | 22 | 1913-1915 | |
| 38 | José Ruiz | 22 | 1901-1914 | |
| 41 | Alarico Rodríguez# | 20 | 1912-1915 | |
| 41 | Marcos Zúñiga | 20 | 1901-1905 | |
| 41 | Roberto Álvarez# | 20 | 1912-1914 | |
| 44 | Francisco Bugarín# | 19 | 1904-1909 | |
| 44 | Pascual Muñoz# | 19 | 1913-1915 | |
| 46 | Calvino Alarcón# | 17 | 1911-1914 | |
| 46 | Henrique Guambe# | 17 | 1914-1915 | |
| 48 | José García# | 16 | 1904-1911 | |
| 48 | Natanael González | 16 | 1901-1910 | |
| 48 | Igor Gómez | 16 | 1901-1909 | |
| 48 | Bill St. George | 16 | 1912-1914 | |
| 52 | Cándido Arellano | 15 | 1901-1905 | |
| 52 | Homero Gómez# | 15 | 1902-1915 | |
| 52 | Venancio Hernández | 15 | 1901-1905 | |
| 52 | Jorge Ramírez | 15 | 1906-1914 | |
| 52 | Ricardo Reyes# | 15 | 1906-1909 | |
| 57 | Pablo Avina | 14 | 1902-1911 | |
| 57 | Heráclito Capellán | 14 | 1901-1911 | |
| 57 | Urías Espinosa | 14 | 1910-1913 | |
| 57 | Eduardo Fernández | 14 | 1901-1911 | |
| 57 | Édgar Jaso | 14 | 1902-1910 | |
| 57 | Cristóbal Mireles# | 14 | 1910-1915 | |
| 57 | Bermudo Ponce | 14 | 1905-1914 | |
| 57 | Hernando Rodríguez# | 14 | 1910-1915 | |
| 57 | Paul Spires | 14 | 1901-1910 | |
| 57 | Esteban Valadés | 14 | 1901-1910 | |
| 67 | Gabriel Calderón | 13 | 1901-1910 | |
| 67 | Ellis Curtis | 13 | 1912-1914 | |
| 67 | Carroll Davis# | 13 | 1914-1915 | |
| 67 | Basilio Macías | 13 | 1907-1913 | |
| 67 | Troilo Martínez | 13 | 1901-1902 | |
| 67 | Diego Paz | 13 | 1901-1906 | |
| 67 | Daniel Quezada | 13 | 1904-1912 | |
| 74 | Dagoberto Arana# | 12 | 1912-1915 | |
| 74 | Próspero Checo | 12 | 1901-1905 | |
| 74 | Matt Deane | 12 | 1901-1908 | |
| 74 | Timoteo Hernández# | 12 | 1912-1915 | |
| 74 | Jesús María Montoya | 12 | 1901-1904 | |
| 74 | Marcelo Morales# | 12 | 1914-1915 | |
| 74 | Marcos Torres# | 12 | 1906-1909 | |
| 81 | Ángel Amparán | 11 | 1901-1904 | |
| 81 | Jesús Barrera# | 11 | 1912-1915 | |
| 81 | Manuel Cepeda | 11 | 1901-1907 | |
| 81 | Juan María Miró# | 11 | 1912-1915 | |
| 81 | Bernal Ortega | 11 | 1901-1907 | |
| 81 | Pelayo Peña | 11 | 1901-1911 | |
| 81 | Gustavo Rodríguez | 11 | 1906-1914 | |
| 81 | Madis Uutma# | 11 | 1915-1915 | |
| 89 | Leovigildo Canales | 10 | 1901-1905 | |
| 89 | Gamaliel Fernández | 10 | 1901-1914 | |
| 89 | Silverio Garzón# | 10 | 1914-1915 | |
| 89 | Heath Jones | 10 | 1901-1912 | |
| 89 | Florent Lebon | 10 | 1910-1915 | |
| 89 | Mateo Pérez# | 10 | 1910-1913 | |
| 89 | Gabe Wright | 10 | 1913-1914 | |
| 89 | Harun Zafir# | 10 | 1912-1915 | |
| 97 | Senén Barrera | 9 | 1911-1915 | |
| 97 | Efraín Camacho | 9 | 1901-1909 | |
| 97 | Orlando Dávila# | 9 | 1906-1912 | |
| 97 | David Morales | 9 | 1904-1914 |
