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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Oscar Soto | 28 | 1903-1913 | |
| 2 | Octavio Álvarez | 17 | 1901-1913 | |
| 3 | Lorenzo Cabrera | 15 | 1901-1911 | |
| 3 | Epifanio Cuenca# | 15 | 1903-1915 | |
| 5 | Florián Sandoval# | 14 | 1905-1914 | |
| 6 | Felipe García | 12 | 1903-1913 | |
| 7 | Osvaldo Rosales# | 10 | 1903-1913 | |
| 7 | Jorge Ruiz | 10 | 1901-1910 | |
| 9 | Latif bin Afif# | 9 | 1913-1915 | |
| 9 | Weston Bourgeois | 9 | 1906-1914 | |
| 9 | Teófilo Espinal# | 9 | 1909-1915 | |
| 9 | Francisco García# | 9 | 1905-1913 | |
| 9 | Matías Martínez# | 9 | 1905-1915 | |
| 9 | Timoteo Muriel# | 9 | 1905-1913 | |
| 9 | Felipe Ramos# | 9 | 1906-1913 | |
| 16 | Juan Padín | 8 | 1901-1910 | |
| 16 | Egidio Rodríguez | 8 | 1901-1914 | |
| 16 | Pablo Villada | 8 | 1902-1913 | |
| 19 | Michael Allan | 7 | 1904-1911 | |
| 19 | Diego Bedolla# | 7 | 1905-1909 | |
| 19 | Carlos Guzmán | 7 | 1901-1906 | |
| 19 | Carlos Salazar# | 7 | 1914-1915 | |
| 23 | José Cisneros# | 6 | 1902-1913 | |
| 23 | Javier Cortez# | 6 | 1906-1909 | |
| 23 | Marcos Guevara | 6 | 1903-1912 | |
| 23 | Juan Medina# | 6 | 1912-1915 | |
| 23 | Símaco Montes | 6 | 1901-1913 | |
| 23 | Jorge Reyes | 6 | 1901-1905 | |
| 23 | Joseph Scott | 6 | 1911-1915 | |
| 23 | Stepán Sindelar# | 6 | 1910-1915 | |
| 31 | Adrián Acosta | 5 | 1901-1909 | |
| 31 | Cirilo Calderón# | 5 | 1911-1911 | |
| 31 | Gelasio Campos# | 5 | 1906-1912 | |
| 31 | Oscar Escalante | 5 | 1901-1904 | |
| 31 | Judá García# | 5 | 1906-1910 | |
| 31 | Noé González | 5 | 1901-1911 | |
| 31 | Adrián Jiménez | 5 | 1901-1905 | |
| 31 | Íñigo León# | 5 | 1902-1915 | |
| 31 | Darío Madrid# | 5 | 1910-1915 | |
| 31 | Luis Martínez# | 5 | 1906-1909 | |
| 31 | Rafael Martínez# | 5 | 1910-1915 | |
| 31 | Diego Navarro# | 5 | 1905-1913 | |
| 31 | Ramón Pagán | 5 | 1902-1913 | |
| 31 | Dalmacio Ramos | 5 | 1903-1915 | |
| 31 | Séptimo Salazar# | 5 | 1912-1915 | |
| 31 | Remigio Vallez# | 5 | 1914-1914 | |
| 47 | Efraín Castro | 4 | 1901-1911 | |
| 47 | Jesús Escobales | 4 | 1902-1912 | |
| 47 | Joaquín Espinosa | 4 | 1901-1906 | |
| 47 | Orlando Figueroa# | 4 | 1912-1915 | |
| 47 | Oscar González# | 4 | 1914-1915 | |
| 47 | Édgar González# | 4 | 1910-1913 | |
| 47 | Frank Groves# | 4 | 1913-1914 | |
| 47 | Bonifacio Martínez# | 4 | 1911-1915 | |
| 47 | Hugo Medrano# | 4 | 1906-1915 | |
| 47 | Anacleto Meléndez | 4 | 1906-1914 | |
| 47 | Julio Morales | 4 | 1901-1909 | |
| 47 | Erasmo Pérez | 4 | 1901-1906 | |
| 47 | Félix Ramírez | 4 | 1904-1911 | |
| 47 | Ulises Ramírez | 4 | 1901-1911 | |
| 47 | Eppa Rixey# | 4 | 1914-1915 | |
| 47 | Santiago Romero | 4 | 1911-1913 | |
| 47 | Telégono Sánchez# | 4 | 1913-1914 | |
| 47 | Brandon Taylor | 4 | 1912-1915 | |
| 47 | Acacio Tejada | 4 | 1901-1911 | |
| 47 | Prudencio Ulloa# | 4 | 1906-1915 | |
| 47 | Rodolfo Valdés# | 4 | 1912-1915 | |
| 47 | Rhys Wilson | 4 | 1906-1914 | |
| 47 | Crisóstomo Yáñez# | 4 | 1911-1915 | |
| 70 | Eusebio Almonte# | 3 | 1914-1915 | |
| 70 | Solón Balcazar# | 3 | 1913-1915 | |
| 70 | Tung Cao# | 3 | 1913-1915 | |
| 70 | Reginaldo Cervantes | 3 | 1901-1912 | |
| 70 | Ewan Cochrane | 3 | 1912-1914 | |
| 70 | Oliver Huerta | 3 | 1901-1906 | |
| 70 | Flavio Inay# | 3 | 1910-1912 | |
| 70 | Catulo Martínez | 3 | 1901-1906 | |
| 70 | Édgar Martínez# | 3 | 1910-1910 | |
| 70 | Morgan Mathews# | 3 | 1915-1915 | |
| 70 | Ignacio Prado# | 3 | 1906-1912 | |
| 70 | Eugenio Pérez# | 3 | 1906-1911 | |
| 70 | Patricio Rodríguez | 3 | 1901-1908 | |
| 70 | Tibulo Rodríguez# | 3 | 1912-1913 | |
| 70 | Marco Antonio Santiago# | 3 | 1911-1915 | |
| 70 | Álvar Silvas# | 3 | 1914-1915 | |
| 70 | Jorge Torres | 3 | 1901-1911 | |
| 70 | Imrich Tosenovsky# | 3 | 1913-1915 | |
| 70 | Telamón Ávila | 3 | 1912-1913 | |
| 89 | Miguel Amaya | 2 | 1901-1913 | |
| 89 | Víctor Andreu# | 2 | 1901-1915 | |
| 89 | Pedro Ayala# | 2 | 1906-1915 | |
| 89 | Ken Boyd | 2 | 1901-1902 | |
| 89 | Bartolomé Carrada | 2 | 1903-1911 | |
| 89 | Oscar Carreno | 2 | 1901-1913 | |
| 89 | Antonio Chatsaga# | 2 | 1915-1915 | |
| 89 | Ross Culp | 2 | 1901-1911 | |
| 89 | Josh Dalton | 2 | 1901-1910 | |
| 89 | Gobrías Delgado | 2 | 1901-1906 | |
| 89 | Virgilio Felán | 2 | 1901-1910 | |
| 89 | Søren Fetterlein# | 2 | 1912-1914 |
