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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Oscar Soto | 372.0 | 1903-1913 | |
| 2 | Octavio Álvarez | 234.0 | 1901-1913 | |
| 3 | Francisco García# | 209.0 | 1905-1913 | |
| 4 | Weston Bourgeois | 181.0 | 1906-1914 | |
| 4 | Florián Sandoval# | 181.0 | 1905-1914 | |
| 6 | Timoteo Muriel# | 166.0 | 1905-1913 | |
| 7 | Ramón Pagán | 161.0 | 1902-1913 | |
| 8 | Egidio Rodríguez | 153.0 | 1901-1914 | |
| 9 | Felipe Ramos# | 148.0 | 1906-1913 | |
| 10 | Felipe García | 146.0 | 1903-1913 | |
| 11 | Lorenzo Cabrera | 145.0 | 1901-1911 | |
| 12 | Marcos Guevara | 138.0 | 1903-1912 | |
| 12 | Matías Martínez# | 138.0 | 1905-1915 | |
| 14 | Pedro Ayala# | 126.0 | 1906-1915 | |
| 15 | Jorge Ruiz | 114.0 | 1901-1910 | |
| 16 | Noé González | 113.0 | 1901-1911 | |
| 17 | Efraín Castro | 112.0 | 1901-1911 | |
| 18 | Osvaldo Rosales# | 111.0 | 1903-1913 | |
| 18 | Pablo Villada | 111.0 | 1902-1913 | |
| 20 | Teófilo Espinal# | 101.0 | 1909-1915 | |
| 20 | Epifanio Cuenca# | 101.0 | 1903-1915 | |
| 22 | Darío Centeno# | 99.0 | 1902-1915 | |
| 23 | Ross Culp | 95.0 | 1901-1911 | |
| 23 | Carlos Caballero | 95.0 | 1903-1912 | |
| 25 | Virgilio Felán | 88.0 | 1901-1910 | |
| 26 | Joaquín Espinosa | 87.0 | 1901-1906 | |
| 27 | Julio Morales | 85.0 | 1901-1909 | |
| 27 | Carlos Guzmán | 85.0 | 1901-1906 | |
| 29 | Elián Lara | 84.0 | 1903-1911 | |
| 30 | Diego Bedolla# | 82.0 | 1905-1909 | |
| 31 | Loquillo Martínez | 81.0 | 1901-1914 | |
| 32 | Gabriel Morales# | 79.0 | 1906-1911 | |
| 32 | Adrián Acosta | 79.0 | 1901-1909 | |
| 34 | Luis Martínez# | 77.0 | 1906-1909 | |
| 35 | Rhys Wilson | 76.0 | 1906-1914 | |
| 36 | Jorge Reyes | 74.0 | 1901-1905 | |
| 37 | Gelasio Campos# | 71.0 | 1906-1912 | |
| 37 | Rafael Martínez# | 71.0 | 1910-1915 | |
| 39 | Latif bin Afif# | 70.0 | 1913-1915 | |
| 40 | Adrián Jiménez | 69.0 | 1901-1905 | |
| 41 | Michael Allan | 67.0 | 1904-1911 | |
| 42 | Emeterio Torres | 66.0 | 1902-1911 | |
| 43 | Hugo Medrano# | 64.0 | 1906-1915 | |
| 43 | Ignacio Prado# | 64.0 | 1906-1912 | |
| 45 | Patricio Rodríguez | 62.0 | 1901-1908 | |
| 46 | Oscar Escalante | 60.0 | 1901-1904 | |
| 47 | Oscar Carreno | 59.0 | 1901-1913 | |
| 48 | Francisco Aguilar# | 58.0 | 1910-1915 | |
| 48 | José Cisneros# | 58.0 | 1902-1913 | |
| 48 | Juan Padín | 58.0 | 1901-1910 | |
| 51 | Eugenio Pérez# | 57.0 | 1906-1911 | |
| 52 | Javier Cortez# | 55.0 | 1906-1909 | |
| 52 | Mike Holtzer | 55.0 | 1901-1904 | |
| 54 | Símaco Montes | 53.0 | 1901-1913 | |
| 54 | Mateo Lugo | 53.0 | 1901-1907 | |
| 54 | Prudencio Ulloa# | 53.0 | 1906-1915 | |
| 54 | Catulo Martínez | 53.0 | 1901-1906 | |
| 58 | Judá García# | 52.0 | 1906-1910 | |
| 58 | Flavio Inay# | 52.0 | 1910-1912 | |
| 58 | Stepán Sindelar# | 52.0 | 1910-1915 | |
| 61 | Édgar González# | 51.0 | 1910-1913 | |
| 61 | Crisóstomo Yáñez# | 51.0 | 1911-1915 | |
| 61 | Dalmacio Ramos | 51.0 | 1903-1915 | |
| 64 | Esteban Baubia# | 48.0 | 1906-1915 | |
| 64 | Diego Navarro# | 48.0 | 1905-1913 | |
| 66 | Erasmo Pérez | 47.0 | 1901-1906 | |
| 67 | Reginaldo Cervantes | 46.0 | 1901-1912 | |
| 67 | Ulises Ramírez | 46.0 | 1901-1911 | |
| 69 | Miguel Díaz | 45.0 | 1904-1906 | |
| 70 | Juan Medina# | 44.0 | 1912-1915 | |
| 70 | Rosario Negrete# | 44.0 | 1911-1914 | |
| 72 | Bartolomé Carrada | 43.0 | 1903-1911 | |
| 73 | Joseph Scott | 42.0 | 1911-1915 | |
| 74 | Jesús Escobales | 41.0 | 1902-1912 | |
| 74 | Cirilo Calderón# | 41.0 | 1911-1911 | |
| 74 | Remigio Vallez# | 41.0 | 1914-1914 | |
| 77 | Acacio Tejada | 40.0 | 1901-1911 | |
| 77 | Frank Groves# | 40.0 | 1913-1914 | |
| 77 | Julio Hernández | 40.0 | 1901-1912 | |
| 77 | Tung Cao# | 40.0 | 1913-1915 | |
| 77 | Carmelo González# | 40.0 | 1906-1912 | |
| 77 | Séptimo Salazar# | 40.0 | 1912-1915 | |
| 83 | Antonio Chatsaga# | 39.0 | 1915-1915 | |
| 84 | Les Haynes | 38.0 | 1907-1911 | |
| 84 | Íñigo León# | 38.0 | 1902-1915 | |
| 86 | Imrich Tosenovsky# | 37.0 | 1913-1915 | |
| 87 | Jesús Sánchez# | 36.0 | 1906-1914 | |
| 87 | Tibulo Rodríguez# | 36.0 | 1912-1913 | |
| 89 | Bonifacio Martínez# | 35.0 | 1911-1915 | |
| 89 | Eppa Rixey# | 35.0 | 1914-1915 | |
| 89 | Félix Ramírez | 35.0 | 1904-1911 | |
| 92 | Brandon Taylor | 34.0 | 1912-1915 | |
| 92 | Santiago Romero | 34.0 | 1911-1913 | |
| 94 | Manuel Barragán | 33.0 | 1902-1912 | |
| 94 | Orlando Figueroa# | 33.0 | 1912-1915 | |
| 94 | Telamón Ávila | 33.0 | 1912-1913 | |
| 94 | Liu-liang Shen# | 33.0 | 1913-1915 | |
| 98 | Vicente Valdez | 32.0 | 1901-1906 | |
| 98 | Anthony Widdowson | 32.0 | 1909-1915 | |
| 98 | Ángel Flores# | 32.0 | 1907-1909 |
