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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K9 | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Stepán Sindelar# | 9.00 | 1910-1915 | |
| 2 | Íñigo León# | 7.98 | 1902-1915 | |
| 3 | José Cisneros# | 7.71 | 1902-1913 | |
| 4 | Tibulo Rodríguez# | 7.50 | 1912-1913 | |
| 5 | Hugo Medrano# | 7.38 | 1906-1915 | |
| 6 | Eppa Rixey# | 7.32 | 1914-1915 | |
| 7 | Anthony Widdowson | 7.24 | 1909-1915 | |
| 8 | Javier Cortez# | 7.16 | 1906-1909 | |
| 9 | Francisco Aguilar# | 7.10 | 1910-1915 | |
| 10 | Matías Martínez# | 7.07 | 1905-1915 | |
| 11 | Prudencio Ulloa# | 6.92 | 1906-1915 | |
| 11 | Frank Groves# | 6.92 | 1913-1914 | |
| 13 | Dalmacio Ramos | 6.88 | 1903-1915 | |
| 14 | Oscar Soto | 6.70 | 1903-1913 | |
| 15 | Crisóstomo Yáñez# | 6.66 | 1911-1915 | |
| 16 | Osvaldo Rosales# | 6.61 | 1903-1913 | |
| 17 | Brandon Taylor | 6.55 | 1912-1915 | |
| 18 | Carmelo González# | 6.53 | 1906-1912 | |
| 19 | Jesús Escobales | 6.48 | 1902-1912 | |
| 20 | Orlando Figueroa# | 6.42 | 1912-1915 | |
| 21 | Remigio Vallez# | 6.37 | 1914-1914 | |
| 22 | Gabriel Morales# | 6.33 | 1906-1911 | |
| 23 | Rafael Martínez# | 6.21 | 1910-1915 | |
| 24 | Bartolomé Carrada | 6.18 | 1903-1911 | |
| 25 | Epifanio Cuenca# | 6.13 | 1903-1915 | |
| 26 | Søren Fetterlein# | 6.00 | 1912-1914 | |
| 26 | Joseph Scott | 6.00 | 1911-1915 | |
| 28 | Imrich Tosenovsky# | 5.97 | 1913-1915 | |
| 29 | Ulises Ramírez | 5.87 | 1901-1911 | |
| 30 | Latif bin Afif# | 5.76 | 1913-1915 | |
| 31 | Jesús Sánchez# | 5.70 | 1906-1914 | |
| 32 | Timoteo Muriel# | 5.64 | 1905-1913 | |
| 33 | Cirilo Calderón# | 5.49 | 1911-1911 | |
| 34 | Felipe Ramos# | 5.45 | 1906-1913 | |
| 35 | Michael Allan | 5.35 | 1904-1911 | |
| 35 | Telamón Ávila | 5.35 | 1912-1913 | |
| 37 | Lorenzo Cabrera | 5.33 | 1901-1911 | |
| 38 | Santiago Romero | 5.29 | 1911-1913 | |
| 39 | Bonifacio Martínez# | 5.05 | 1911-1915 | |
| 40 | Teófilo Espinal# | 4.96 | 1909-1915 | |
| 41 | Tung Cao# | 4.95 | 1913-1915 | |
| 42 | Judá García# | 4.85 | 1906-1910 | |
| 43 | Efraín Castro | 4.81 | 1901-1911 | |
| 44 | Diego Navarro# | 4.66 | 1905-1913 | |
| 45 | Ramón Pagán | 4.51 | 1902-1913 | |
| 46 | Ignacio Prado# | 4.48 | 1906-1912 | |
| 46 | Pedro Ayala# | 4.48 | 1906-1915 | |
| 48 | Pablo Villada | 4.46 | 1902-1913 | |
| 49 | Egidio Rodríguez | 4.45 | 1901-1914 | |
| 50 | Rhys Wilson | 4.36 | 1906-1914 | |
| 51 | Octavio Álvarez | 4.34 | 1901-1913 | |
| 52 | Liu-liang Shen# | 4.32 | 1913-1915 | |
| 53 | Rosario Negrete# | 4.30 | 1911-1914 | |
| 54 | Manuel Barragán | 4.28 | 1902-1912 | |
| 55 | Carlos Caballero | 4.17 | 1903-1912 | |
| 56 | Juan Medina# | 4.06 | 1912-1915 | |
| 57 | Florián Sandoval# | 4.03 | 1905-1914 | |
| 58 | Erasmo Pérez | 4.02 | 1901-1906 | |
| 59 | Oscar Carreno | 3.97 | 1901-1913 | |
| 60 | Les Haynes | 3.96 | 1907-1911 | |
| 61 | Felipe García | 3.94 | 1903-1913 | |
| 62 | Mateo Lugo | 3.88 | 1901-1907 | |
| 63 | Luis Martínez# | 3.86 | 1906-1909 | |
| 64 | Weston Bourgeois | 3.81 | 1906-1914 | |
| 65 | Noé González | 3.73 | 1901-1911 | |
| 66 | Reginaldo Cervantes | 3.66 | 1901-1912 | |
| 66 | Édgar González# | 3.66 | 1910-1913 | |
| 68 | Loquillo Martínez | 3.65 | 1901-1914 | |
| 69 | Julio Morales | 3.57 | 1901-1909 | |
| 70 | Acacio Tejada | 3.54 | 1901-1911 | |
| 71 | Esteban Baubia# | 3.51 | 1906-1915 | |
| 71 | Jorge Reyes | 3.51 | 1901-1905 | |
| 73 | Carlos Guzmán | 3.48 | 1901-1906 | |
| 74 | Patricio Rodríguez | 3.45 | 1901-1908 | |
| 75 | Francisco García# | 3.40 | 1905-1913 | |
| 76 | Darío Centeno# | 3.35 | 1902-1915 | |
| 77 | Marcos Guevara | 3.31 | 1903-1912 | |
| 78 | Ross Culp | 3.29 | 1901-1911 | |
| 78 | Adrián Acosta | 3.29 | 1901-1909 | |
| 80 | Catulo Martínez | 3.23 | 1901-1906 | |
| 81 | Símaco Montes | 3.19 | 1901-1913 | |
| 82 | Antonio Chatsaga# | 3.18 | 1915-1915 | |
| 83 | Séptimo Salazar# | 3.15 | 1912-1915 | |
| 84 | Félix Ramírez | 3.09 | 1904-1911 | |
| 85 | Jorge Ruiz | 2.90 | 1901-1910 | |
| 86 | Elián Lara | 2.87 | 1903-1911 | |
| 87 | Virgilio Felán | 2.85 | 1901-1910 | |
| 88 | Emeterio Torres | 2.83 | 1902-1911 | |
| 89 | Julio Hernández | 2.68 | 1901-1912 | |
| 90 | Gelasio Campos# | 2.65 | 1906-1912 | |
| 91 | Vicente Valdez | 2.51 | 1901-1906 | |
| 92 | Mike Holtzer | 2.45 | 1901-1904 | |
| 92 | Adrián Jiménez | 2.45 | 1901-1905 | |
| 94 | Joaquín Espinosa | 2.38 | 1901-1906 | |
| 95 | Juan Padín | 2.33 | 1901-1910 | |
| 96 | Oscar Escalante | 2.25 | 1901-1904 | |
| 96 | Ángel Flores# | 2.25 | 1907-1909 | |
| 96 | Flavio Inay# | 2.25 | 1910-1912 | |
| 99 | Eugenio Pérez# | 2.21 | 1906-1911 | |
| 100 | Diego Bedolla# | 1.63 | 1905-1909 |
