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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | SO | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Roberto Marín# | 85 | 1903-1914 | |
| 2 | Édgar Doñate# | 78 | 1903-1914 | |
| 2 | Francis March# | 78 | 1903-1914 | |
| 4 | Arquímedes Guevara# | 74 | 1904-1914 | |
| 5 | Martín Castillo# | 63 | 1907-1914 | |
| 6 | Iapeto García# | 61 | 1903-1914 | |
| 7 | Zacarías Tijerina# | 58 | 1903-1914 | |
| 8 | Nuño Yañes# | 57 | 1903-1914 | |
| 9 | Francisco Macedo# | 44 | 1903-1914 | |
| 9 | Big Bill Smith | 44 | 1903-1911 | |
| 11 | Jorge Saldierna# | 43 | 1903-1914 | |
| 11 | Ignacio Valdez# | 43 | 1903-1914 | |
| 13 | Danger Talbert# | 42 | 1903-1914 | |
| 14 | Casimiro Amarante# | 39 | 1903-1914 | |
| 14 | Enrique Morales# | 39 | 1903-1914 | |
| 16 | Andrés Maldonado# | 38 | 1907-1914 | |
| 17 | Atanasio Peñaflor# | 36 | 1903-1910 | |
| 18 | Chris Holmes# | 35 | 1905-1914 | |
| 18 | Cristóbal Yépez# | 35 | 1903-1914 | |
| 20 | René Zúñiga# | 33 | 1906-1914 | |
| 21 | Hansel Ibarra# | 32 | 1903-1914 | |
| 21 | Jeremías Morales# | 32 | 1903-1914 | |
| 21 | Adriel Suárez# | 32 | 1906-1914 | |
| 24 | B. Dopazo# | 31 | 1903-1914 | |
| 24 | Fielder Jones | 31 | 1903-1906 | |
| 26 | Ginés Elizarrarás# | 30 | 1903-1914 | |
| 26 | Will Lawton | 30 | 1903-1910 | |
| 26 | Gilberto Torres# | 30 | 1903-1914 | |
| 29 | Pascual Castellanos | 29 | 1904-1914 | |
| 29 | Belasco Martínez# | 29 | 1904-1914 | |
| 29 | Édgar Moral# | 29 | 1906-1914 | |
| 29 | Avelino Pérez# | 29 | 1907-1914 | |
| 33 | Élouan Besson# | 28 | 1906-1914 | |
| 33 | Gobrías Emeric# | 28 | 1903-1914 | |
| 33 | Pedro Gaspar# | 28 | 1906-1914 | |
| 36 | Serafín García# | 27 | 1903-1914 | |
| 36 | Roberto Martínez# | 27 | 1906-1914 | |
| 36 | Homero Méndez# | 27 | 1906-1914 | |
| 39 | Luis Becerra | 26 | 1903-1914 | |
| 39 | Jack Johnson# | 26 | 1903-1914 | |
| 41 | Glen Brown | 25 | 1904-1914 | |
| 41 | Belerofón Escobar# | 25 | 1908-1914 | |
| 41 | Berengario González# | 25 | 1903-1914 | |
| 41 | Espártaco Martín | 25 | 1903-1913 | |
| 41 | Howard Neville# | 25 | 1905-1914 | |
| 41 | Cormick Sweeney# | 25 | 1904-1914 | |
| 47 | Gabriel Arroyo# | 24 | 1905-1914 | |
| 47 | Luis Bustamante# | 24 | 1905-1914 | |
| 47 | Ángel Rodríguez# | 24 | 1903-1914 | |
| 50 | Gilberto Cruz | 23 | 1903-1914 | |
| 50 | Heliodoro Hidalgo# | 23 | 1903-1914 | |
| 50 | Diomedes Lucio# | 23 | 1905-1914 | |
| 50 | Lucio Madrid# | 23 | 1905-1914 | |
| 50 | Harrison Scott# | 23 | 1905-1914 | |
| 55 | Marco Chacón# | 22 | 1903-1914 | |
| 55 | Beloveso Corchado# | 22 | 1903-1914 | |
| 55 | Nicholas Fleming# | 22 | 1906-1911 | |
| 55 | Leo Infante | 22 | 1903-1911 | |
| 55 | Candy LaChance# | 22 | 1903-1914 | |
| 55 | Emmett Seery | 22 | 1903-1907 | |
| 61 | Harry Buckner# | 21 | 1903-1914 | |
| 61 | Jorge Espinosa# | 21 | 1906-1914 | |
| 61 | Prisco Florido# | 21 | 1903-1914 | |
| 61 | Tácito Piñeda# | 21 | 1905-1914 | |
| 61 | Esdras Álvarez# | 21 | 1903-1914 | |
| 66 | Harry Allen# | 20 | 1903-1914 | |
| 66 | Bryan DeWitt | 20 | 1903-1907 | |
| 66 | Mateo Díaz# | 20 | 1903-1914 | |
| 66 | Raúl Gallegos | 20 | 1903-1912 | |
| 66 | Derek Larkin | 20 | 1906-1914 | |
| 66 | Marcos Madrid# | 20 | 1903-1914 | |
| 66 | Euríalo Manzano# | 20 | 1906-1914 | |
| 66 | Pablo Morales | 20 | 1903-1914 | |
| 66 | Martín Toro | 20 | 1903-1910 | |
| 75 | Saturnín Luna# | 19 | 1905-1914 | |
| 75 | Símaco Navarro# | 19 | 1903-1914 | |
| 75 | Estanislao Velázquez# | 19 | 1903-1914 | |
| 75 | Octavio Zúñiga# | 19 | 1903-1914 | |
| 79 | Ed Abbaticchio# | 18 | 1903-1914 | |
| 79 | Conrado Arias | 18 | 1903-1909 | |
| 79 | Alfredo Baró# | 18 | 1903-1914 | |
| 79 | Eduardo Hernández# | 18 | 1904-1914 | |
| 79 | Carlos La Guardia# | 18 | 1903-1914 | |
| 79 | Pedro López | 18 | 1903-1910 | |
| 79 | Alberto Medina# | 18 | 1904-1914 | |
| 79 | Atenágoras Sánchez# | 18 | 1903-1914 | |
| 79 | Ciriaco Álvarez# | 18 | 1905-1914 | |
| 88 | Emilio Bello# | 17 | 1903-1914 | |
| 88 | Derek Day# | 17 | 1906-1914 | |
| 88 | Tarasio Granados# | 17 | 1908-1914 | |
| 88 | Mórsimo Hernández# | 17 | 1906-1914 | |
| 88 | Esteban Lois | 17 | 1903-1913 | |
| 88 | Aimar Ochoa# | 17 | 1907-1914 | |
| 88 | Absalón Topete# | 17 | 1911-1914 | |
| 95 | Joe Flynn | 16 | 1903-1910 | |
| 95 | Laertes Gallardo# | 16 | 1903-1914 | |
| 95 | Bill Galloway | 16 | 1903-1914 | |
| 95 | Menandro López# | 16 | 1903-1914 | |
| 95 | Jorge Martínez | 16 | 1903-1913 | |
| 95 | Natán Morán# | 16 | 1911-1914 |
