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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Christy Mathewson# | 267 | 1903 | |
| 2 | Frank Groves# | 253 | 1905 | |
| 3 | Frank Groves# | 252 | 1904 | |
| 4 | Jack Chesbro | 239 | 1904 | |
| 5 | Charlie Geggus | 231 | 1901 | |
| 6 | Tom Hughes | 225 | 1901 | |
| 7 | Christy Mathewson# | 221 | 1901 | |
| 8 | Christy Mathewson# | 212 | 1904 | |
| 9 | Eddie Plank | 210 | 1905 | |
| 9 | Frank Groves# | 210 | 1906 | |
| 11 | Christy Mathewson# | 206 | 1905 | |
| 11 | Joe Corbett# | 206 | 1901 | |
| 13 | Justin Huber# | 203 | 1906 | |
| 14 | Eddie Plank | 201 | 1904 | |
| 15 | Joe Corbett# | 196 | 1906 | |
| 16 | Justin Huber# | 195 | 1904 | |
| 17 | Justin Huber# | 193 | 1905 | |
| 18 | Egyptian Healy | 186 | 1901 | |
| 19 | Doc White | 185 | 1902 | |
| 20 | Will Sawyer | 177 | 1901 | |
| 21 | Eddie Plank | 176 | 1903 | |
| 21 | Jim Handiboe | 176 | 1903 | |
| 23 | Emmett Bowman# | 173 | 1910 | |
| 24 | Joe McGinnity | 171 | 1903 | |
| 25 | Toad Ramsey | 164 | 1907 | |
| 26 | Les German | 163 | 1901 | |
| 26 | Peek-A-Boo Veach | 163 | 1901 | |
| 28 | Will Sawyer | 161 | 1903 | |
| 29 | Christy Mathewson# | 159 | 1902 | |
| 29 | Justin Huber# | 159 | 1910 | |
| 29 | Pink Hawley# | 159 | 1904 | |
| 32 | Joe Corbett# | 158 | 1905 | |
| 33 | Bert Abbey | 157 | 1910 | |
| 34 | John Truan# | 156 | 1906 | |
| 34 | Charlie Geggus | 156 | 1902 | |
| 34 | Jack Chesbro | 156 | 1905 | |
| 34 | Joe Corbett# | 156 | 1902 | |
| 38 | Joe Corbett# | 155 | 1908 | |
| 38 | Justin Huber# | 155 | 1907 | |
| 40 | Joe Corbett# | 153 | 1907 | |
| 41 | Joe Corbett# | 152 | 1903 | |
| 41 | Jack Chesbro | 152 | 1906 | |
| 43 | Jim St. Vrain# | 151 | 1904 | |
| 44 | Case Patten | 150 | 1904 | |
| 44 | Charles Bender# | 150 | 1905 | |
| 46 | Tom Hughes | 149 | 1905 | |
| 46 | Bob Black | 149 | 1905 | |
| 46 | Joe Corbett# | 149 | 1904 | |
| 49 | Will Sawyer | 148 | 1904 | |
| 49 | Earl Moore | 148 | 1903 | |
| 49 | Egyptian Healy | 148 | 1904 | |
| 52 | Justin Huber# | 147 | 1908 | |
| 52 | Jack Chesbro | 147 | 1903 | |
| 54 | Jesse Burkett | 146 | 1906 | |
| 54 | Charlie Geggus | 146 | 1903 | |
| 56 | Charles Bender# | 145 | 1906 | |
| 56 | Ed Morris | 145 | 1901 | |
| 58 | Pink Hawley# | 144 | 1905 | |
| 58 | Joe McGinnity | 144 | 1904 | |
| 58 | Bert Abbey | 144 | 1909 | |
| 58 | Frank Harrison# | 144 | 1910 | |
| 58 | Scott Stratton# | 144 | 1905 | |
| 63 | Carl Lundgren# | 143 | 1904 | |
| 64 | Egyptian Healy | 141 | 1902 | |
| 64 | Andy Coakley# | 141 | 1906 | |
| 64 | Brent Mattern# | 141 | 1909 | |
| 67 | Matt Kilroy | 140 | 1901 | |
| 68 | John Truan# | 139 | 1903 | |
| 68 | Earl Moore | 139 | 1904 | |
| 68 | Bob Black | 139 | 1906 | |
| 71 | Jesse Burkett | 138 | 1904 | |
| 71 | Frank Groves# | 138 | 1907 | |
| 71 | Brent Mattern# | 138 | 1904 | |
| 74 | Frank Groves# | 137 | 1909 | |
| 74 | George Mullin# | 137 | 1905 | |
| 74 | Scott Stratton# | 137 | 1906 | |
| 77 | Bill Daley | 136 | 1906 | |
| 77 | Jack Chesbro | 136 | 1902 | |
| 77 | Fritz Clausen | 136 | 1904 | |
| 77 | Scott Stratton# | 136 | 1904 | |
| 77 | Christy Mathewson# | 136 | 1913 | |
| 82 | Bob Black | 135 | 1904 | |
| 82 | George Mullin# | 135 | 1906 | |
| 82 | Brent Mattern# | 135 | 1906 | |
| 82 | John Alder# | 135 | 1909 | |
| 86 | Egyptian Healy | 134 | 1905 | |
| 86 | Brent Mattern# | 134 | 1910 | |
| 86 | Abner Powell | 134 | 1904 | |
| 89 | Case Patten | 133 | 1903 | |
| 89 | Jake Campbell# | 133 | 1909 | |
| 89 | Deacon Phillippe | 133 | 1905 | |
| 92 | Doc White | 132 | 1901 | |
| 93 | Jake Campbell# | 131 | 1910 | |
| 93 | Adam Briggs# | 131 | 1909 | |
| 93 | Earl Moore | 131 | 1905 | |
| 96 | Babe Adams# | 129 | 1910 | |
| 96 | Jack Chesbro | 129 | 1901 | |
| 96 | Frank Groves# | 129 | 1908 | |
| 99 | Christy Mathewson# | 128 | 1906 | |
| 100 | Egyptian Healy | 127 | 1906 |
