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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | SO | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Luis Ríos# | 60 | 1901-1913 | |
| 2 | Pedro Flores# | 57 | 1905-1913 | |
| 3 | Brendan Lea | 56 | 1901-1913 | |
| 4 | Hortensio Hernández# | 44 | 1902-1913 | |
| 4 | Feliciano Rodríguez | 44 | 1901-1911 | |
| 6 | Emanuel Velázquez# | 39 | 1904-1913 | |
| 7 | Auliffe Moore# | 37 | 1904-1913 | |
| 8 | Luis Alfaro# | 36 | 1903-1913 | |
| 9 | Edelmiro Pichardo# | 31 | 1901-1913 | |
| 10 | Segundo Villanueva | 30 | 1901-1913 | |
| 11 | Salvador Moreno# | 28 | 1902-1913 | |
| 12 | Abdul-Ghaffar bin Ayyub# | 27 | 1907-1913 | |
| 13 | Aristarco Cortez | 26 | 1901-1911 | |
| 13 | Pandolfo Freyre | 26 | 1901-1908 | |
| 15 | Bill McAleer# | 25 | 1905-1913 | |
| 15 | Miqueas Velásquez# | 25 | 1908-1913 | |
| 17 | Eufemio Hernández# | 24 | 1905-1913 | |
| 17 | Bill Lelivelt# | 24 | 1909-1913 | |
| 17 | Martín Morales# | 24 | 1904-1913 | |
| 17 | Pablo Niño# | 24 | 1905-1913 | |
| 17 | Heráclito Sosa# | 24 | 1902-1913 | |
| 22 | Humberto Dimas | 23 | 1901-1913 | |
| 22 | Jorge Lacayo# | 23 | 1904-1913 | |
| 24 | Tomás Candelario# | 22 | 1904-1913 | |
| 24 | Evaristo Flores# | 22 | 1906-1913 | |
| 26 | Polifemo Carrasco# | 21 | 1907-1913 | |
| 26 | René Díaz# | 21 | 1905-1913 | |
| 26 | George Hampson# | 21 | 1908-1913 | |
| 29 | Filippio Aglietti# | 20 | 1908-1913 | |
| 29 | Belerofonte Báez# | 20 | 1903-1913 | |
| 29 | Abdón Farías# | 20 | 1903-1913 | |
| 29 | Honorio Hernandes# | 20 | 1905-1913 | |
| 33 | Etelfrido Tenesaca# | 19 | 1904-1913 | |
| 34 | Normando Fraire# | 18 | 1906-1913 | |
| 34 | Manuel Hinojosa# | 18 | 1907-1913 | |
| 34 | Abdón Jara | 18 | 1901-1907 | |
| 37 | Roberto Aguilar | 17 | 1901-1904 | |
| 37 | Huáscar Angulo# | 17 | 1901-1913 | |
| 37 | Carlos Moreno# | 17 | 1904-1913 | |
| 37 | Bonifacio Sánchez# | 17 | 1905-1913 | |
| 37 | Anaxímenes Vásquez# | 17 | 1908-1913 | |
| 42 | Sebastián Castillo# | 16 | 1903-1913 | |
| 42 | Agüeybaná Durango | 16 | 1901-1911 | |
| 42 | Armando Marsans# | 16 | 1905-1913 | |
| 42 | Silverio Martínez# | 16 | 1904-1913 | |
| 42 | Natanael Montes# | 16 | 1907-1913 | |
| 42 | Marco Antonio Murillo# | 16 | 1904-1913 | |
| 42 | Plinio Reyes | 16 | 1901-1908 | |
| 49 | Diego Arroliga# | 15 | 1905-1913 | |
| 49 | Ismael Huerta | 15 | 1902-1911 | |
| 49 | Geoffrey Leitermann# | 15 | 1908-1913 | |
| 49 | Gabriel Quijano# | 15 | 1903-1913 | |
| 53 | Ricardo Chávez | 14 | 1901-1907 | |
| 53 | Arsenio García# | 14 | 1904-1913 | |
| 53 | Efraín Loaíza | 14 | 1901-1912 | |
| 53 | Efraín Lorona# | 14 | 1905-1913 | |
| 53 | Santiago Rocha | 14 | 1901-1913 | |
| 53 | Juan Álvarez | 14 | 1901-1906 | |
| 59 | Bernardo Concepción# | 13 | 1901-1913 | |
| 59 | Filóxenos Díaz# | 13 | 1905-1913 | |
| 59 | Casiodoro Herrera# | 13 | 1902-1913 | |
| 59 | Farón Rodríquez# | 13 | 1901-1913 | |
| 59 | Álvaro Sánchez | 13 | 1902-1913 | |
| 59 | Scannell Taylor# | 13 | 1906-1913 | |
| 59 | Noé Valerio# | 13 | 1901-1913 | |
| 66 | Oscar Abrego# | 12 | 1904-1913 | |
| 66 | Kayne Ariss# | 12 | 1906-1913 | |
| 66 | Jorge Astacio# | 12 | 1907-1913 | |
| 66 | Javier Barrera# | 12 | 1908-1913 | |
| 66 | Gonzalo García# | 12 | 1904-1913 | |
| 66 | Lino Martinez# | 12 | 1911-1913 | |
| 66 | Conor Milward | 12 | 1901-1908 | |
| 66 | Brock O'Connell# | 12 | 1907-1913 | |
| 66 | Alex Parker | 12 | 1901-1906 | |
| 66 | Tomás Piñeda# | 12 | 1905-1912 | |
| 66 | Guadalupe Ramos | 12 | 1901-1911 | |
| 66 | Edelmiro Rodríguez# | 12 | 1904-1913 | |
| 66 | Abejundio Ríos | 12 | 1903-1912 | |
| 79 | Demóstenes Amador# | 11 | 1904-1913 | |
| 79 | Tom Barnes | 11 | 1901-1911 | |
| 79 | Luis Campos# | 11 | 1908-1913 | |
| 79 | Bienvenido Carrillo | 11 | 1904-1911 | |
| 79 | Santiago Díaz | 11 | 1901-1910 | |
| 79 | Carlos Escobar# | 11 | 1907-1913 | |
| 79 | Fructuoso Gaspar# | 11 | 1904-1913 | |
| 79 | Nicolás Grijalva | 11 | 1901-1910 | |
| 79 | Ryan Joseph | 11 | 1903-1907 | |
| 79 | Víctor Macías | 11 | 1901-1905 | |
| 79 | Santiago Mireles# | 11 | 1901-1913 | |
| 79 | Balbino Mojica# | 11 | 1905-1913 | |
| 79 | Manuel Rosales# | 11 | 1905-1913 | |
| 79 | Gilberto Suárez | 11 | 1901-1907 | |
| 79 | Gabriel Zelaya | 11 | 1901-1905 | |
| 94 | Édgar Alvarado | 10 | 1903-1913 | |
| 94 | Atilano Castaño# | 10 | 1902-1913 | |
| 94 | Luis Echeverría | 10 | 1901-1901 | |
| 94 | Anatolio Eusebio# | 10 | 1906-1913 | |
| 94 | Agamenón Gloria | 10 | 1903-1913 | |
| 94 | Amentario Guzmán# | 10 | 1905-1913 | |
| 94 | Jesús Jaramillo | 10 | 1901-1910 |
