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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Normando Fraire# | 1.002 | 1906 | |
| 2 | Agapito Mejía# | 1.054 | 1904 | |
| 3 | Casiodoro Herrera# | 1.319 | 1907 | |
| 4 | Abdón Farías# | 1.334 | 1905 | |
| 5 | Pedro Chavarría | 1.365 | 1903 | |
| 6 | Ryan Joseph | 1.416 | 1903 | |
| 7 | Ismael Pérez | 1.441 | 1903 | |
| 8 | Juan Rodríguez# | 1.446 | 1913 | |
| 9 | Semónides Flores | 1.485 | 1903 | |
| 10 | Luis Pérez | 1.495 | 1903 | |
| 11 | Amadís Pérez# | 1.497 | 1906 | |
| 12 | Natalino Hernández# | 1.520 | 1909 | |
| 13 | Antonio Maldonado# | 1.525 | 1904 | |
| 14 | Bill Lelivelt# | 1.544 | 1909 | |
| 15 | Abdón Farías# | 1.552 | 1906 | |
| 16 | Scannell Taylor# | 1.556 | 1913 | |
| 17 | Murrough Reynolds# | 1.573 | 1912 | |
| 18 | Tomás Piñeda# | 1.574 | 1907 | |
| 19 | Eugenio Aranda# | 1.578 | 1908 | |
| 20 | Henry Wilkin | 1.607 | 1903 | |
| 21 | Dacio Colón | 1.614 | 1903 | |
| 22 | Mariano Sandoval# | 1.619 | 1913 | |
| 23 | Desiderio Pérez# | 1.637 | 1903 | |
| 24 | Eusebio Pacheco | 1.667 | 1903 | |
| 25 | Gervasio Reynaga# | 1.671 | 1903 | |
| 26 | Javier Olivarez# | 1.685 | 1913 | |
| 27 | Bill Lelivelt# | 1.692 | 1913 | |
| 28 | Luis Espada | 1.702 | 1902 | |
| 29 | Kayne Ariss# | 1.709 | 1906 | |
| 30 | Luis Rivera# | 1.711 | 1907 | |
| 31 | Emanuel Vallejos# | 1.715 | 1905 | |
| 32 | Orestes Enríquez | 1.721 | 1903 | |
| 33 | Abdón Farías# | 1.753 | 1904 | |
| 34 | Casiodoro Herrera# | 1.756 | 1904 | |
| 35 | Marcos Arias# | 1.757 | 1904 | |
| 36 | Báquides Alvarado# | 1.759 | 1906 | |
| 37 | Ricardo Hernández# | 1.761 | 1910 | |
| 38 | José Figueroa | 1.764 | 1904 | |
| 39 | Héctor Montes# | 1.772 | 1903 | |
| 40 | Benjamin McDougall | 1.777 | 1903 | |
| 41 | Atilano Castaño# | 1.782 | 1906 | |
| 42 | Ismael Pérez | 1.796 | 1905 | |
| 43 | Santiago Rocha | 1.804 | 1904 | |
| 44 | Casiodoro Herrera# | 1.817 | 1905 | |
| 45 | Abdón Farías# | 1.821 | 1903 | |
| 46 | Santiago Carmona | 1.825 | 1903 | |
| 47 | Casiodoro Herrera# | 1.832 | 1909 | |
| 48 | Ismael Huerta | 1.835 | 1903 | |
| 49 | Guadalupe Ramos | 1.837 | 1902 | |
| 50 | Guadalupe Ramos | 1.838 | 1903 | |
| 51 | Geoff McAfee | 1.846 | 1903 | |
| 52 | Amadís Pérez# | 1.848 | 1903 | |
| 53 | Sergio Ríos# | 1.856 | 1906 | |
| 54 | Elía Chavira | 1.859 | 1903 | |
| 55 | Mo Tuck# | 1.864 | 1912 | |
| 56 | Lucio Colón | 1.865 | 1906 | |
| 56 | Ricardo Pinto# | 1.865 | 1907 | |
| 58 | Ismael Pérez | 1.872 | 1906 | |
| 59 | Héctor Arellano# | 1.876 | 1912 | |
| 60 | Agapito Mejía# | 1.882 | 1903 | |
| 61 | Manuel Zendejas# | 1.885 | 1906 | |
| 62 | Ryan Joseph | 1.893 | 1907 | |
| 62 | Marcos Arias# | 1.893 | 1905 | |
| 64 | Benjamin McDougall | 1.899 | 1907 | |
| 64 | Héctor Montes# | 1.899 | 1907 | |
| 66 | Luis Pérez | 1.901 | 1904 | |
| 67 | Noé Valerio# | 1.902 | 1903 | |
| 68 | Oscar Gutiérrez | 1.910 | 1903 | |
| 69 | Ismael Huerta | 1.918 | 1907 | |
| 70 | Emanuel Vallejos# | 1.925 | 1907 | |
| 71 | Murrough Reynolds# | 1.929 | 1913 | |
| 72 | Juan Rodríguez# | 1.931 | 1908 | |
| 73 | Hernán Cruz# | 1.938 | 1903 | |
| 74 | Jairo Salinas# | 1.942 | 1906 | |
| 75 | Quilvio Montúfar | 1.950 | 1903 | |
| 75 | Miguel Govea# | 1.950 | 1903 | |
| 77 | Theo Ellis | 1.953 | 1903 | |
| 77 | Edelmiro Orihuela# | 1.953 | 1903 | |
| 79 | Natalino Hernández# | 1.958 | 1903 | |
| 80 | Gonzalo García# | 1.968 | 1907 | |
| 81 | Farón Rodríquez# | 1.972 | 1904 | |
| 82 | Amadís Pérez# | 1.973 | 1909 | |
| 83 | Hernán Cruz# | 1.975 | 1913 | |
| 84 | Desiderio Pérez# | 1.976 | 1906 | |
| 85 | Víctor Rivera# | 1.980 | 1907 | |
| 86 | Agüeybaná García | 1.984 | 1903 | |
| 87 | Anaxímenes Rodríguez# | 1.986 | 1910 | |
| 88 | Ismael Huerta | 1.987 | 1904 | |
| 89 | Velimir Marinković# | 1.989 | 1913 | |
| 90 | Lucio Colón | 1.993 | 1904 | |
| 91 | Petronio Linares# | 1.995 | 1905 | |
| 92 | Perseo Salgado# | 1.996 | 1906 | |
| 93 | Cristóbal Savala | 2.000 | 1901 | |
| 94 | Miguel Domínguez | 2.004 | 1903 | |
| 95 | Miguel Escobar# | 2.006 | 1910 | |
| 96 | Matías Alberti | 2.007 | 1903 | |
| 97 | Sílvano Mata | 2.010 | 1903 | |
| 97 | Fernando Bracamonte | 2.010 | 1902 | |
| 99 | Esteban Quiros | 2.011 | 1903 | |
| 100 | Noé Valerio# | 2.013 | 1901 |
