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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Félix Loño# | 264 | 1904-1915 | |
| 2 | Timoteo Contreras# | 240 | 1907-1915 | |
| 3 | Moose McCormick# | 231 | 1904-1915 | |
| 4 | Osiris Mena# | 218 | 1904-1915 | |
| 5 | George Wright# | 210 | 1904-1914 | |
| 6 | Eugenio Murillo# | 207 | 1907-1915 | |
| 7 | M. Izquierdo# | 191 | 1904-1915 | |
| 7 | J. Matas# | 191 | 1904-1915 | |
| 9 | Narciso Arrieta# | 190 | 1904-1915 | |
| 10 | Jesús García# | 188 | 1905-1915 | |
| 11 | Orran Lewis# | 186 | 1904-1915 | |
| 12 | Ginés Aguilar# | 152 | 1905-1915 | |
| 13 | Sófocles Díaz# | 151 | 1904-1915 | |
| 14 | Édgar Salazar# | 147 | 1904-1915 | |
| 15 | Curcio Torres# | 143 | 1906-1915 | |
| 16 | Esteban Navarro# | 141 | 1909-1915 | |
| 17 | Diego Santos# | 139 | 1904-1915 | |
| 18 | Luis Díaz# | 137 | 1906-1915 | |
| 19 | Isidro Escudero# | 121 | 1906-1915 | |
| 20 | Ernesto Toala# | 114 | 1910-1915 | |
| 21 | Pete Hill# | 112 | 1904-1915 | |
| 21 | G. Vidal# | 112 | 1904-1915 | |
| 23 | Elijah Mann | 105 | 1904-1915 | |
| 23 | Juan Rubio# | 105 | 1912-1915 | |
| 25 | Ernesto Arúz# | 102 | 1904-1915 | |
| 26 | Juan Centeno# | 97 | 1906-1915 | |
| 27 | Doroteo Santizo# | 96 | 1909-1915 | |
| 28 | Joe Cassidy# | 93 | 1904-1915 | |
| 29 | Fernando Castillo# | 92 | 1905-1915 | |
| 30 | Andrónico Castillo# | 91 | 1904-1915 | |
| 30 | Micah James# | 91 | 1905-1915 | |
| 30 | Luis Rivas# | 91 | 1904-1915 | |
| 30 | Héctor Ríos# | 91 | 1905-1915 | |
| 34 | François Bellet# | 89 | 1906-1915 | |
| 34 | Agamenón Díaz# | 89 | 1904-1915 | |
| 36 | Richard Compton | 87 | 1907-1915 | |
| 37 | Gabriel Martínez# | 84 | 1905-1915 | |
| 38 | Bill Stuart | 83 | 1904-1914 | |
| 39 | Chris Gridley# | 81 | 1905-1915 | |
| 40 | Ángel Pérez# | 80 | 1909-1915 | |
| 41 | Jack Stivetts | 79 | 1904-1914 | |
| 42 | Alejo Martínez# | 76 | 1906-1915 | |
| 42 | Eufemio Palacios# | 76 | 1912-1915 | |
| 44 | Mateo Torres# | 75 | 1909-1915 | |
| 45 | Pedro Olave# | 74 | 1904-1915 | |
| 45 | Frank Schulte# | 74 | 1904-1915 | |
| 47 | Alfredo Pérez# | 73 | 1904-1915 | |
| 47 | Uriel Álvarez# | 73 | 1906-1915 | |
| 49 | Bill Keats | 72 | 1905-1915 | |
| 49 | Alberto Martín# | 72 | 1904-1915 | |
| 51 | Chad McNeil# | 70 | 1905-1915 | |
| 51 | Josh Petrone# | 70 | 1905-1915 | |
| 53 | Tarasio Ruiz# | 69 | 1904-1915 | |
| 54 | Telmo Machado# | 68 | 1909-1915 | |
| 54 | Valeriano Pérez# | 68 | 1904-1915 | |
| 56 | Jeremy Juriga# | 67 | 1905-1915 | |
| 57 | Juan Pérez# | 66 | 1906-1915 | |
| 58 | Alejandro Hernández# | 65 | 1906-1915 | |
| 58 | Quinn Hurst# | 65 | 1905-1915 | |
| 58 | Natán Quezada# | 65 | 1906-1915 | |
| 61 | Terry DeGrand# | 64 | 1905-1915 | |
| 61 | Luis Martínez# | 64 | 1904-1915 | |
| 61 | Santiago Placencia# | 64 | 1910-1915 | |
| 64 | Nehemías Piñeda# | 63 | 1906-1915 | |
| 65 | José López# | 62 | 1906-1915 | |
| 65 | Juan Meza# | 62 | 1905-1915 | |
| 67 | Alberto Briseño# | 61 | 1907-1915 | |
| 67 | Rob Mohl# | 61 | 1905-1915 | |
| 67 | Bill Shore# | 61 | 1905-1915 | |
| 70 | Chris Coryea# | 60 | 1905-1915 | |
| 70 | Edward Fisher# | 60 | 1905-1915 | |
| 70 | León Garza# | 60 | 1912-1915 | |
| 70 | Divino Marcial# | 60 | 1905-1915 | |
| 70 | Richard Schanowski | 60 | 1905-1915 | |
| 70 | Ben Walcott# | 60 | 1905-1915 | |
| 76 | Nicolás Rosales# | 59 | 1906-1915 | |
| 76 | Induciomaro Ávila# | 59 | 1907-1914 | |
| 78 | Farzad Hajar# | 58 | 1905-1915 | |
| 78 | René Pedroza# | 58 | 1905-1915 | |
| 78 | Álvaro Preciado | 58 | 1904-1912 | |
| 78 | Nick Sebastian# | 58 | 1905-1915 | |
| 82 | Ossan Bruntoun# | 57 | 1906-1915 | |
| 82 | Claudio Gutiérrez# | 57 | 1907-1915 | |
| 82 | Bill Latour | 57 | 1905-1915 | |
| 85 | Mike Bredenkamp# | 56 | 1905-1915 | |
| 85 | Mike Hall# | 56 | 1905-1914 | |
| 85 | Elton Stevenson | 56 | 1905-1915 | |
| 88 | Agapito González# | 55 | 1906-1915 | |
| 88 | Vidal López# | 55 | 1905-1915 | |
| 90 | Lázaro Fresneda# | 54 | 1904-1915 | |
| 90 | Jon Schaffer# | 54 | 1905-1915 | |
| 92 | Halim bin Ishaq# | 53 | 1909-1915 | |
| 92 | Steve Collins# | 53 | 1905-1915 | |
| 92 | Balbino Fornaris# | 53 | 1905-1915 | |
| 92 | Toomey McLoughlin# | 53 | 1907-1915 | |
| 92 | Jim Schaff# | 53 | 1905-1915 | |
| 92 | Cristián Urdialez# | 53 | 1904-1915 | |
| 92 | Tomás Velásquez# | 53 | 1909-1915 | |
| 99 | Jimeno Carranza# | 52 | 1906-1915 | |
| 99 | Jesús Carrillo# | 52 | 1906-1915 |
