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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Félix Loño# | 264 | 1904-1915 | |
| 2 | George Wright# | 210 | 1904-1914 | |
| 3 | Juan Centeno# | 97 | 1906-1915 | |
| 4 | Doroteo Santizo# | 96 | 1909-1915 | |
| 5 | Luis Rivas# | 91 | 1904-1915 | |
| 6 | François Bellet# | 89 | 1906-1915 | |
| 7 | Tarasio Ruiz# | 67 | 1904-1915 | |
| 8 | Juan Pérez# | 66 | 1906-1915 | |
| 9 | Quinn Hurst# | 65 | 1905-1915 | |
| 10 | Alberto Briseño# | 61 | 1907-1915 | |
| 11 | Farzad Hajar# | 58 | 1905-1915 | |
| 12 | Chris Kaiser# | 51 | 1905-1915 | |
| 12 | Acasto Quiroz# | 51 | 1906-1915 | |
| 14 | Tobías Lamas# | 50 | 1904-1915 | |
| 15 | Craig Martin# | 48 | 1905-1915 | |
| 16 | Tomás Uribe# | 44 | 1911-1915 | |
| 17 | Onesíforo Gutiérrez# | 38 | 1909-1915 | |
| 18 | Frank Blake | 35 | 1904-1914 | |
| 18 | Jimeno Carranza# | 35 | 1906-1915 | |
| 18 | Luis Fernández# | 35 | 1906-1915 | |
| 18 | Tomás Meda# | 35 | 1905-1915 | |
| 22 | Aaron Winans# | 31 | 1904-1915 | |
| 23 | Simon Allen# | 30 | 1905-1915 | |
| 23 | Grant Johnson# | 30 | 1904-1905 | |
| 25 | Dana Vessey | 29 | 1905-1915 | |
| 25 | Antonio Villa# | 29 | 1905-1915 | |
| 27 | Paul Winters# | 25 | 1905-1915 | |
| 28 | Jesús Aguilar | 24 | 1904-1914 | |
| 28 | Generoso Maldonado# | 24 | 1910-1915 | |
| 30 | Premislao Haro# | 22 | 1904-1915 | |
| 30 | Elton Stevenson | 22 | 1905-1915 | |
| 32 | Santiago Salinas# | 21 | 1906-1915 | |
| 33 | Taylor Stubbs | 19 | 1911-1914 | |
| 34 | Sebastián Bustamante# | 18 | 1905-1915 | |
| 35 | Joe Curtis# | 16 | 1905-1915 | |
| 35 | Grant Underhill | 16 | 1905-1915 | |
| 35 | Albert York | 16 | 1905-1915 | |
| 38 | Felipe Farías# | 15 | 1905-1915 | |
| 38 | Filóstrato López# | 15 | 1904-1915 | |
| 40 | Luis Coronado# | 14 | 1911-1915 | |
| 40 | Judson Fleury | 14 | 1905-1915 | |
| 40 | Beltrán Juárez# | 14 | 1907-1915 | |
| 40 | Dennis Perry | 14 | 1904-1915 | |
| 40 | Alistair Ross# | 14 | 1905-1915 | |
| 45 | Sebastián Cantú# | 13 | 1904-1915 | |
| 45 | Procopio Guzmán# | 13 | 1911-1915 | |
| 45 | Tomás Jiménez# | 13 | 1911-1915 | |
| 45 | Rob Mohl# | 13 | 1905-1915 | |
| 45 | Francisco Santa Cruz# | 13 | 1904-1915 | |
| 50 | Clemente Estrada# | 12 | 1904-1915 | |
| 50 | Elijah Ross# | 12 | 1905-1915 | |
| 52 | Benedicto Jaén# | 11 | 1912-1915 | |
| 53 | Harry Aubrey# | 10 | 1904-1915 | |
| 53 | Alejandro Ortiz# | 10 | 1904-1915 | |
| 55 | Frank Kent# | 9 | 1905-1912 | |
| 55 | Cristián Urdialez# | 9 | 1904-1915 | |
| 57 | Myles Norton# | 8 | 1905-1915 | |
| 57 | Nicolás Vizcarra# | 8 | 1905-1915 | |
| 59 | Andrónico Castillo# | 7 | 1904-1915 | |
| 59 | Matías Garza# | 7 | 1906-1909 | |
| 59 | Gumersindo Veloz# | 7 | 1914-1915 | |
| 62 | Valeriano Luján# | 6 | 1908-1915 | |
| 62 | Divino Marcial# | 6 | 1905-1915 | |
| 62 | Martín Salazar | 6 | 1906-1915 | |
| 65 | Belisario Benavides# | 5 | 1906-1915 | |
| 65 | Eddie Brûlé | 5 | 1906-1915 | |
| 65 | Daryl Gough | 5 | 1904-1915 | |
| 65 | Cecilio López# | 5 | 1904-1915 | |
| 65 | Devlin Randell | 5 | 1905-1914 | |
| 65 | Jorge Vega | 5 | 1904-1912 | |
| 71 | Francisco Martínez# | 4 | 1906-1915 | |
| 71 | Bryan Reilly | 4 | 1905-1915 | |
| 73 | Fulvio Abineri# | 3 | 1912-1915 | |
| 73 | Ludovico Altamirano# | 3 | 1915-1915 | |
| 73 | Tom Cahill | 3 | 1904-1908 | |
| 73 | Aimón Cruz# | 3 | 1909-1915 | |
| 73 | Pelayo Rodríguez# | 3 | 1906-1910 | |
| 78 | Pedro Amado | 2 | 1904-1904 | |
| 78 | Narciso Arrieta# | 2 | 1904-1915 | |
| 78 | Polinario Díaz# | 2 | 1906-1915 | |
| 78 | Adam Krofft# | 2 | 1905-1915 | |
| 78 | Héctor Morel# | 2 | 1905-1915 | |
| 78 | Alfredo Navratil# | 2 | 1915-1915 | |
| 78 | Dale Oloff# | 2 | 1905-1915 | |
| 78 | Belisario Portillo# | 2 | 1906-1915 | |
| 78 | Nicandro Rodríguez# | 2 | 1906-1915 | |
| 78 | Virgilio Tapia | 2 | 1906-1915 | |
| 78 | Joe Tinker | 2 | 1904-1904 | |
| 89 | Samuel Alvarado | 1 | 1904-1911 | |
| 89 | Jimmy Bannon | 1 | 1904-1906 | |
| 89 | Manuel Bautista# | 1 | 1906-1915 | |
| 89 | Curtis Carlin# | 1 | 1905-1915 | |
| 89 | Celino Carrillo | 1 | 1905-1915 | |
| 89 | Pedro Castañeda | 1 | 1904-1911 | |
| 89 | Derek Cooley# | 1 | 1905-1915 | |
| 89 | Ismael Cota# | 1 | 1910-1915 | |
| 89 | Rich Crowner# | 1 | 1905-1915 | |
| 89 | Benedicto Gómez# | 1 | 1906-1915 | |
| 89 | Steve Kruse# | 1 | 1905-1915 | |
| 89 | Logan Lyon# | 1 | 1905-1915 |
